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Relative dosimetrical verification in high dose rate brachytherapy using two-dimensional detector array IMatriXX

机译:使用二维探测器阵列IMatriXX的高剂量率近距离放射治疗中的相对剂量学验证

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摘要

For high dose rate (HDR) brachytherapy, independent treatment verification is needed to ensure that the treatment is performed as per prescription. This study demonstrates dosimetric quality assurance of the HDR brachytherapy using a commercially available two-dimensional ion chamber array called IMatriXX, which has a detector separation of 0.7619 cm. The reference isodose length, step size, and source dwell positional accuracy were verified. A total of 24 dwell positions, which were verified for positional accuracy gave a total error (systematic and random) of –0.45 mm, with a standard deviation of 1.01 mm and maximum error of 1.8 mm. Using a step size of 5 mm, reference isodose length (the length of 100% isodose line) was verified for single and multiple catheters of same and different source loadings. An error ≤1 mm was measured in 57% of tests analyzed. Step size verification for 2, 3, 4, and 5 cm was performed and 70% of the step size errors were below 1 mm, with maximum of 1.2 mm. The step size ≤1 cm could not be verified by the IMatriXX as it could not resolve the peaks in dose profile.
机译:对于高剂量率(HDR)近距离治疗,需要进行独立的治疗验证,以确保按照处方进行治疗。这项研究证明了使用市售的二维离子室阵列IMatriXX进行的HDR近距离放射治疗的剂量学质量保证,该阵列的检测器间距为0.7619 cm。参考等剂量长度,步长和源驻留位置的准确性得到了验证。经验证位置精度的总共24个驻留位置给出的总误差(系统误差和随机误差)为–0.45 mm,标准偏差为1.01 mm,最大误差为1.8 mm。使用5 mm的步长,对相同和不同来源负荷的单个和多个导管,验证了参考等剂量长度(等剂量线长度为100%)。在分析的57%的测试中,测得的误差≤1mm。进行了2、3、4和5厘米的步长验证,并且70%的步长误差小于1毫米,最大为1.2毫米。 IMatriXX无法验证步长≤1 cm,因为它无法解析剂量曲线中的峰。

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